Allergy<\/a> szakfoly\u00f3iratban jelent meg.<\/p>\n\u201eOlyan bab\u00e1kat vizsg\u00e1ltunk, akik id\u0151re sz\u00fclettek, komplik\u00e1ci\u00f3mentes v\u00e1rand\u00f3ss\u00e1gb\u00f3l cs\u00e1sz\u00e1rmetsz\u00e9ssel. Ut\u00f3bbi az\u00e9rt volt fontos, mert a term\u00e9szetes m\u00f3don val\u00f3 sz\u00fclet\u00e9s gyullad\u00e1sos v\u00e1laszt v\u00e1lt ki az immunrendszerb\u0151l, \u00e9s ez zavarta volna az eredm\u00e9nyek \u00e9rt\u00e9kel\u00e9s\u00e9t \u2013 mondja Toldi Gergely. \u2013 K\u00f6zvetlen\u00fcl a megsz\u00fclet\u00e9s\u00fck ut\u00e1n v\u00e9rt \u00e9s sz\u00e9kletmint\u00e1t vett\u00fcnk a csecsem\u0151kt\u0151l, majd h\u00e1romhetes korukban ezt megism\u00e9telt\u00fck. Vizsg\u00e1ltuk, hogy a T-limfocit\u00e1k (immunsejtek) hogyan v\u00e1ltoznak az els\u0151 hetekben, \u00e9s a baba immunsejtjei hogyan reag\u00e1lnak az anyai sejtekre.\u201d<\/p>\n
A terhess\u00e9g idej\u00e9n anyai sejtek jutnak a magzatba a m\u00e9hlep\u00e9nyen kereszt\u00fcl, majd a megsz\u00fclet\u00e9se ut\u00e1n az anyatejjel a b\u00e9lrendszer\u00e9n kereszt\u00fcl is jut be az any\u00e1t\u00f3l sz\u00e1rmaz\u00f3 sejt a gyermek v\u00e9rkering\u00e9s\u00e9be. A kutat\u00f3 szerint eddig egy\u00e1lt\u00e1l\u00e1n nem volt ismert, hogy ez immunol\u00f3giai szempontb\u00f3l mit jelent, milyen reakci\u00f3kat v\u00e1lt ki. Minthogy a b\u00e9lmikrobiom kutat\u00e1sa az ut\u00f3bbi \u00e9vtizedekben nagyon dinamikusan fejl\u0151dik, a b\u00e9lbakt\u00e9riumok \u00f6sszet\u00e9tel\u00e9t is vizsg\u00e1lt\u00e1k anyatejes bab\u00e1kn\u00e1l, illetve kontrollk\u00e9nt haszn\u00e1lt t\u00e1pszeres t\u00e1rsaikn\u00e1l.<\/p>\n
\u201eAz eredm\u00e9nyeink azt mutatj\u00e1k, hogy az els\u0151 h\u00e1rom h\u00e9tben jelent\u0151s v\u00e1ltoz\u00e1s t\u00f6rt\u00e9nik a szerzett immunit\u00e1sban. Erre az\u00e9rt nem volt eddig emberekt\u0151l sz\u00e1rmaz\u00f3 adat, mert neh\u00e9z kutat\u00e1si c\u00e9lra v\u00e9rmint\u00e1t venni eg\u00e9szs\u00e9ges \u00fajsz\u00fcl\u00f6ttekt\u0151l. Az ismereteink ez\u00e9rt f\u0151k\u00e9nt \u00e1llatk\u00eds\u00e9rletekb\u0151l sz\u00e1rmaznak \u2013 folytatja a neonatol\u00f3gus. \u2013 A szab\u00e1lyz\u00f3 T-sejtek mennyis\u00e9g\u00e9nek k\u00fcl\u00f6nbs\u00e9ge kifejezetten jelent\u0151s az anyatejes \u00e9s a t\u00e1pszeres bab\u00e1k k\u00f6z\u00f6tt.<\/p>\n
Arr\u00f3l ezek az eredm\u00e9nyek k\u00f6zvetlen\u00fcl nem adnak inform\u00e1ci\u00f3t, hogy a tapasztalt k\u00fcl\u00f6nbs\u00e9geknek van-e hat\u00e1suk a bab\u00e1k eg\u00e9szs\u00e9gi \u00e1llapot\u00e1ra, betegs\u00e9geikre, az immunrendszer\u00fck k\u00e9s\u0151bbi helyt\u00e1ll\u00e1s\u00e1ra. A kutat\u00f3k hossz\u00fa t\u00e1von tervezik, hogy nyomon k\u00f6vetik e gyermekek fejl\u0151d\u00e9s\u00e9t. Az\u00e9rt d\u00f6nt\u00f6ttek \u00fagy jelen esetben, hogy eg\u00e9szen kis korban, h\u00e1romhetesen veszik le a csecsem\u0151kt\u0151l a m\u00e1sodik v\u00e9rmint\u00e1t, mert Angli\u00e1ban ekkor m\u00e9g nem kapnak k\u00f6telez\u0151 olt\u00e1sokat (a BCG sem k\u00f6telez\u0151 ott), \u00edgy kev\u00e9s olyan k\u00fcls\u0151 k\u00f6r\u00fclm\u00e9nnyel kell sz\u00e1molni, ami befoly\u00e1soln\u00e1 az immunrendszer\u00fcket az anyatejen k\u00edv\u00fcl. M\u00e1s epidemiol\u00f3giai vizsg\u00e1latokb\u00f3l azonban tudhat\u00f3, hogy a szab\u00e1lyz\u00f3 T-sejtekn\u00e9l jellemz\u0151 v\u00e1ltoz\u00e1s tapasztalhat\u00f3 az allergi\u00e1sokn\u00e1l, az autoimmun betegekn\u00e9l \u00e9s a fert\u0151z\u00e9sen \u00e1tesettekn\u00e9l.<\/p>\n
Nem ismert az sem, hogy a h\u00e1romhetes korban tapasztalt t\u00f6bb szab\u00e1lyz\u00f3 T-sejt vajon tart\u00f3s k\u00fcl\u00f6nbs\u00e9get jelez, vagy sz\u00e1muk r\u00f6vid id\u0151n bel\u00fcl kiegyenl\u00edt\u0151dik az anyatejes \u00e9s a t\u00e1pszeres bab\u00e1k k\u00f6z\u00f6tt. A kutat\u00f3 meg\u00e9rz\u00e9se szerint bizonyos m\u00e9rt\u00e9kig val\u00f3sz\u00edn\u0171leg kiegyenl\u00edt\u0151dik a k\u00e9s\u0151bbi \u00e9letszakaszban, de a korai t\u00f6rt\u00e9n\u00e9sek ett\u0151l f\u00fcggetlen\u00fcl fontosak maradhatnak a hossz\u00fa t\u00e1v\u00fa immunfejl\u0151d\u00e9s szempontj\u00e1b\u00f3l.<\/p>","protected":false},"excerpt":{"rendered":"
A Birminghami Egyetem kutat\u00f3i Toldi Gergely, az Immunol\u00f3giai \u00e9s Immunter\u00e1pi\u00e1s Int\u00e9zet munkat\u00e1rsa \u00e9s a Fiatal Kutat\u00f3k Akad\u00e9mi\u00e1j\u00e1nak tagja vezet\u00e9s\u00e9vel kimutatt\u00e1k, hogy az anyatejjel t\u00e1pl\u00e1lt bab\u00e1k immunrendszer\u00e9ben \u00e9let\u00fck els\u0151 het\u00e9ben t\u00f6bb szab\u00e1lyoz\u00f3 T-sejt jelenik meg, mint a t\u00e1pszeres bab\u00e1k\u00e9ban.<\/p>","protected":false},"author":8,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"cikk_cimkek":[25],"content_flags":[],"content_icons":[],"class_list":["post-12382","post","type-post","status-publish","format-standard","hentry","category-erdmost","cikk_cimkek-mindennapok"],"acf":[],"_links":{"self":[{"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/posts\/12382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/comments?post=12382"}],"version-history":[{"count":0,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/posts\/12382\/revisions"}],"wp:attachment":[{"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/media?parent=12382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/categories?post=12382"},{"taxonomy":"cikk_cimkek","embeddable":true,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/cikk_cimkek?post=12382"},{"taxonomy":"content_flags","embeddable":true,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/content_flags?post=12382"},{"taxonomy":"content_icons","embeddable":true,"href":"https:\/\/erdmost.hu\/en\/wp-json\/wp\/v2\/content_icons?post=12382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}